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Hande Güçlü
This 30YO male presented with persistent decreased vision in his left eye two months following blunt ocular trauma. While incarcerated, he sustained blunt head and ocular trauma during a physical assault resulting in his head striking a bunk bed. Vision was counting fingers OS.
Fundus photography shows a diamond-shaped giant macular hole. Following vitrectomy, internal limiting membrane peeling, and silicone oil, vision improved to 20/200 with a residual open macular hole.
J Vitreoretin Dis. 2026 Apr 14:24741264261432178. doi: 10.1177/24741264261432178.
Post-PDR PPV Long-term patient survival rates stable over the prior 2 decades, despite advances in diabetic care. Survival rates 89% 3-year, 81% 5-year, 81% 10-year — Retrospective, TriNetX database
Purpose: To provide updated survival data for patients with proliferative diabetic retinopathy (PDR) undergoing pars plana vitrectomy (PPV) and identify associated prognostic factors.
Methods: An aggregated electronic health records research network was used to identify patients with a diagnosis of PDR who underwent PPV between 2009 and 2019 and a control group of patients with PDR without a history of PPV. Groups were propensity score matched for age, sex, race, ethnicity, and HbA1c. Main outcomes included survival rates at 3, 5, and 10 years using the Kaplan-Meier life table method. Additional analyses were performed to assess if survival rates differed in patients with PDR by PPV indication (vitreous hemorrhage [VH] or tractional retinal detachment [TRD]).
Results: A total of 8637 patients were included. The 3-, 5-, and 10-year survival rates in patients with PDR after PPV were 89.2%, 80.9%, and 52.8%, respectively. Survival rates in patients with PDR with a history of PPV vs without a history of PPV were lower at 3 (88.7% vs 89.9%; P = .03), 5 (80.2% vs 82.6%; P < .01), and 10 years (51.4% vs 55.8%; P < .01). Survival rates were similar between patients who underwent PPV for VH or TRD at 3 (90.4% vs 88.7%; P = .05), 5 (82.7% vs 81.0%; P = .10), and 10 years (53.0% vs 53.4%; P = .75).
Conclusions: Despite major advances in diabetes care, the long-term survival rates in patients with PDR after PPV have remained stable the last 2 decades, emphasizing the need for multidisciplinary evaluation and prompt cardiovascular and renal optimization.
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