This 44YO female with a diagnosis of chronic anterior uveitis in the left eye presented with visual acuity of 20/60 and cystoid macular edema recalcitrant to topical and periocular steroids. We treated her with an intravitreal dexamethasone implant (Ozurdex).
Optos imaging one week later revealed an unusual vertical orientation of the implant, ‘standing proud’ near the optic disc within the posterior vitreous. There was no prior pars plana vitrectomy surgery.
Even in non-vitrectomized eyes, an Ozurdex implant may take a vertical position within the vitreous and not attach to the peripheral retina as it usually does. The patient was asymptomatic, and observation was recommended.

