This 52YO female has a 10-year history of breast cancer and a 3-year history of metastatic pulmonary disease, which is controlled with systemic chemotherapy. She was referred for an asymptomatic lesion in her right eye.
Fundus photography shows an amelanotic subretinal lesion inferonasal to the nerve. This lesion faintly hyper-autofluoresces.
OCT scanning through this lesion shows a thickened choroid with a somewhat undulating overlying RPE and shallow subretinal fluid.
Learning Points:
Although uveal melanoma is the most common primary intraocular malignancy, metastatic choroidal tumors are the most common intraocular malignancies. Lung and breast cancer are the most common sources. These lesions can be treated with systemic chemotherapy and are also usually very responsive to external beam radiation.
After discussing the findings with her oncologist, the lesion will be treated with external beam radiation.
