This patient, previously treated for proliferative diabetic retinopathy with panretinal photocoagulation (PRP), presented with an asymptomatic resolving two-toned subhyaloid hemorrhage. The devitalized yellow blood indicates chronicity, although some red blood remains.
The OCT confirms the subhyaloid location of the hyperreflective blood.
Red blood is dark on fundus autofluorescence (FAF), although yellow blood is extremely hyperautofluorescent. Lipofuscin within the RPE is the main fluorophore in FAF. The laser PRP scars are hypoautofluorescent due to loss of the RPE.

