This 49YO female’s retinal vasculature was initially creamy white from very high triglycerides.
After 8 months of systemic treatment, her triglyceride levels normalized, her blood turned back to its normal red color, and her retinal vessels normalized in appearance.
Learning Points:
Lipemia retinalis is a rare retinal manifestation of severe hypertriglyceridemia, characterized by creamy white discoloration of the retinal vasculature. In severe cases, the fundus can turn salmon-colored.
Patients are asymptomatic, and vision is normal. However, they are at obvious cardiovascular risk without systemic treatment.

