This 77YO female presented for routine examination on 2/7/25 with asymptomatic degenerative retinoschisis (DRS) inferotemporally in her left eye. When she returned one year later, the schisis had completely spontaneously flattened.
Learning Points:
The dynamics of DRS cavities were noted by Byer in 1972 when he reported the first case of spontaneous regression (Arch Ophthalmology 1972;88:207-209). Since adopting UWF imaging in our practice, we have found that schisis is often not static, with DRS enlarging or flattening. Inner- and outer-layer breaks also appear over time, often independent of changes in the schisis cavity.
