Retina. 2026 Mar 1;46(3):417-424. doi: 10.1097/IAE.0000000000004710.
Summary
ICSC Fingerprint pattern (peripheral portion of serous detachment in OPL on en face) is present in 18% of eyes. Retrospective, 120 eyes.
Abstract
Purpose: To evaluate the prevalence of retinal fingerprint pattern (RFP) in central serous chorioretinopathy (CSCR) and its association with the anatomical and clinical characteristics of the disease.
Methods: In this cross-sectional retrospective study, we included patients with active chronic and acute CSCR. The presence and distribution of RFP was evaluated based on macular 6-mm optical coherence tomography angiography scan pattern. To display RFP structural en face projections of a slab between two segmentation lines of the outer plexiform layer 20 µ m apart, set at the border between outer plexiform and outer nuclear layers were used. Correlation between the presence of RFP and clinical and demographical parameters and anatomical outcomes was evaluated.
Results: After evaluation of 120 CSCR eyes, 22 eyes (18.3%) with RFP were identified. The presence of RFP was associated with higher baseline best-corrected visual acuity, central retinal thickness, subretinal fluid (SRF) height, the degree of neurosensory retina bending at the edge of the neurosensory detachment, and the area of the neurosensory detachment ( P < 0.05). Complete SRF resolution, either spontaneously or after laser treatment, was observed in 68.2% eyes with RFP and 36.8% eyes without RFP ( P = 0.03). No cases demonstrated RFP after resolution of SRF.
Conclusion: Using en face optical coherence tomography imaging RFP can be observed in a significant proportion of CSCR eyes. The presence of RFP is associated with a higher amount of SRF and more favorable anatomical outcomes. The RFP in CSCR resulted from mechanical deformation of the retina by SRF and has a reversible character.
