In this patient’s right eye, there is a classic sharp margin between perfused and nonperfused retina. The fellow eye (not pictured) is relatively normal.
Angiography shows some vascular leakage at the margin of the perfused and nonperfused retina.
Ultra-widefield imaging in our practice has dramatically increased the detection of Eale’s disease.
Learning Points:
Eales’ disease is an idiopathic peripheral occlusive vasculopathy that can cause retinal neovascularization and vitreous hemorrhage.
It is characterized by peripheral sharply circumscribed regions of ischemia, often with retinal neovascularization at the junction of perfused and ischemic retina.

