This 41YO female presented with vision of 20/70 OD and 20/25 OS from bilateral retinal vasculitis, highlighted well on fluorescein angiogram.
Extensive workup was negative, including sarcoidosis (chest X-ray, ACE, lysozyme), ANCA, ANA, HLA-B27, Lyme, and RPR. Following the negative labs, she was started on oral prednisone 20mg/day.
Learning Points:
Idiopathic Retinitis, Vasculitis, Aneurysms, and Neuroretinitis (IRVAN) is a rare disease of unknown etiology characterized by retinal vasculitis, aneurysmal arterial dilations, and neuroretinitis. The diagnosis is clinical, as there are no systemic associations or diagnostic laboratory tests.
Retinal vasculitis can be seen in a number of conditions, including pars planitis, frosted branch angiitis, lupus vasculitis, Behcet’s, and idiopathic retinal vasculitis aneurysms and neuroretinitis (IRVAN).
