This patient had been followed for age-related macular degeneration (AMD) with bilateral confluent soft drusen. She then developed a large acquired vitelliform lesion overlying a retinal pigment epithelial detachment (PED) in her right eye. There are several PEDs also shown in the left eye.
Learning Points:
Vitelliform lesions are commonly found with other disorders, including retinal dystrophies (Best’s disease and macular dystrophies), cuticular drusen, AMD, and vitreomacular traction.
The yellow subretinal material is felt to be debris from shed photoreceptor outer segments. These lesions markedly autofluoresce on fundus autofluorescence.
A great reference to learn more about AVLs is Freund et al Retina 2011;31:13-25.
