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X-LINKED RETINOSCHISIS

Originally posted on @retina.rocks 04/11/2022

This 39YO male presented to our clinic with a known history of sex-linked retinoschisis. Vision was 20/100 OU.

Optos color and green channel images show faint radiating foveal cystic changes bilaterally (only right eye shown).

Swept-source OCT scanning shows prominent splitting of the inner nuclear layer.

Learning Points:

Although historically taught as involving the nerve fiber layer, sex-linked retinoschisis in the posterior pole causes schisis throughout the macula including the inner nuclear, outer nuclear and outer plexiform layers (see Yu et al, AJO 2010;149:973-978).

With time, the schisis often collapses with secondary atrophy (see Menke et al, Retina 2011;31:1186-1192).