CHOROIDEREMIA
This 14YO male is surprisingly asymptomatic with visual acuity of 20/30 OD and 20/40 OS. His retinal findings were found on a routine exam. Optos imaging shows large symmetrically bilateral scalloped areas of chorioretinal atrophy, which spare the central maculas. On fundus fluorescein angiography, the early phase (middle) shows exquisite detail of the choroidal vortex… Read More
CHOROIDAL NEVUS
This 58YO male was initially seen in 2001 with a small asymptomatic choroidal nevus superior to the right optic nerve. He presented to us in 2022 with a still asymptomatic but much enlarged nevus. The lesion now extends to the nerve. There is no overlying orange pigment or subretinal fluid clinically or on OCT. The… Read More
CHORIORETINAL FOLDS
This 75YO female presented with 20/25 vision OU and asymptomatic chorioretinal folds. Optos color imaging shows extensive, irregularly oriented and oblique chorioretinal folds. Learning Points: Chorioretinal folds appear clinically as often subtle horizontal and oblique subretinal folds. There are extensive intra- and extra-ocular causes for these folds. Typical findings include a mild to moderate hyperopic… Read More
MULTIFOCAL CHOROIDITIS
This 58YO male has stable vision of 20/20 OD and light perception OS. Extensive areas of subretinal fibrosis are scattered throughout each fundus, left greater than right. A hyperreflective subfoveal scar on OCT in his left eye accounts for the poor vision. Fortunately, the right macula is relatively normal, and we are observing him twice… Read More
AIRBAG TRAUMA
This 35YO male presented with a unilateral swollen nerve and retinal striae following blunt trauma from airbag deployment Vision was 20/25. The intraocular pressure was 15, and there were no signs of open-globe injury. Optos imaging shows retinal folds radiating from the macular center. These striae are also evident on the OCT thickness map. He… Read More
CARBOPLATIN TOXICITY
This patient, undergoing chemotherapy with carboplatin, developed these scattered nerve fiber layer infarcts (cotton wool spots). Learning Points: Carboplatin is an alkylating agent used to treat various cancers, including ovarian, lung, head and neck, brain, and neuroblastoma. Retinal ischemia and optic neuropathies can rarely be found in patients taking both high-dose and cumulative-dose intravenous therapy…. Read More
PERSISTENT FETAL VASCULATURE
This 48YO male gave a history of blindness in his right eye since birth. Vision was no light perception. The anterior chamber was shallow with a stalk of tissue radiating from the nerve to the back of his crystalline lens. The macula was hypoplastic. The left eye was completely normal. Learning Points: Persistent fetal vasculature… Read More
RETINAL BREAK
This 50YO female presented with sudden vision loss and floaters in her left eye. Despite the presence of the vitreous hemorrhage, we were able to adequately visualize the causative break and surround it with cryotherapy (not pictured). A week later, the vitreous hemorrhage increased, and vitrectomy was performed. At the time of surgery, the vitreoretinal… Read More
HYDROXYCHLOROQUINE TOXICITY
This 73YO female presented with bilateral hydroxychloroquine (Plaquenil) macular toxicity despite being treated for only 5 years. Vision was 20/40 OD and 20/30 OS. Color photography shows very subtle pigmentary changes encircling each fovea. Fundus autofluorescence (FAF) shows subtle changes as well. The findings are most evident with OCT, which shows symmetrical paracentral outer retinal… Read More
PENTOSAN POLYSULFATE SODIUM MACULOPATHY
This 64YOF presented in February 2020 with findings of Pentosan polysulfate sodium (PPS, Elmiron) retinal toxicity. She used PPS for 4 years, but discontinued the drug 9 years earlier. We have since followed her yearly. Optos color imaging of the prior (17 months earlier) and current examinations shows variable yellow-orange atrophic macular pigmentary changes. These… Read More

