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This 44YO male with a known history of sickle cell disease was referred for a possible detached retina. Vision has decreased over the past few years. Vision was 20/200 OU. Optos color RGB imaging shows a large area of active neovascularization in the right temporal midperiphery associated with extensive angiographic retinal ischemia. Similar ischemia is… Read More

This 54YO male presented for a second opinion with several weeks of progressive bilateral painless vision loss. He gave a history of active pulmonary tuberculosis, diagnosed about 6 months earlier, which was being treated with antitubercular therapy (ATT) including ethambutol. There was also a 5-year history of well-controlled type 2 diabetes. Vision was 20/200 OU…. Read More

This 31YO postpartum female presented with sudden vision loss 3 days following delivery, which was complicated by severe preeclampsia (blood pressure was up to systolic 215 mmHg). Vision was 20/50 bilaterally. Optos color RG imaging shows bilateral subretinal yellow bands and drusen-like changes. OCT shows disruption of the outer retinal bands with variable amorphous hyperreflective… Read More

This 42YO female has been followed by us for 7 years with a known history of Bietti crystalline retinopathy with homozygosity for a pathogenic CYP4V2 variant. Vision was stable at 20/400 OU. Fundus imaging shows extensive pigmentary degeneration with subretinal crystalline deposits involving both posterior poles. The crystalline deposits are best seen on near-infrared imaging…. Read More

This healthy 16YO male was referred for an asymptomatic lesion in his left eye. Vision was 20/20 in his normal OD and 20/50 OS. Triton color imaging shows a foveal hyperpigmented lesion with a nasal and superior rim of more intense pigmentation. Triton swept-source OCT shows a markedly hyperreflective intraretinal lesion that protrudes above the… Read More

This 55YO diabetic male presented with 2 months of bilateral vision loss. Vision was 20/80 OD and 20/120 OS. Pseudocolor SLO ultrawidefield imaging of his left eye shows moderate asteroid hyalosis, with larger condensed stands of material obscuring the underlying macula. Spectral domain OCT scanning shows complex variable vitreous traction on the disc and macula… Read More

This healthy 5YO boy presented with decreased vision and repetitive eye movements. Family history was negative. Vision was 20/200 OU. Low-amplitude horizontal nystagmus was noted bilaterally. MultiColor imaging shows star-shaped macular atrophy OD with a more rounded area of atrophy OS. OCT shows complete central RPE and outer retinal atrophy. A homozygous pathogenic missense mutation… Read More

This healthy 39YO female gave a history 18 years earlier of prior anti-VEGF therapy OD for ocular histoplasmosis. She was visually asymptomatic, and vision was 20/40 OD and 20/30 OS. Color photography of her left eye shows a patchy area of pigment loss in the superonasal fovea. OCT scanning through this area shows a choroidal… Read More

This 53YO female presented with gradual bilateral vision loss. Three years earlier, she was treated elsewhere for metastatic breast carcinoma, which included a mastectomy followed by radiotherapy to the supraclavicular region and brain. She denied having diabetes. Vision was 20/60 OD and 20/30 OS. Fundus photography shows bilateral macular telangiectasia with radiating macular lipid flecks…. Read More

This 57YO female with a history of severe hypertension presented with one day of severe vision loss in her right eye. Blood pressure was 200/100 mmHg. Vision was hand motion OD and 20/20 in her normal OS. MultiColor SLO imaging shows inner retinal opacification sparing the macular center, consistent with a fresh central retinal artery… Read More