NON-PROLIFERATIVE DIABETIC RETINOPATHY (NPDR)
This 69YO female with a history of type 2 diabetes was referred for asymptomatic retinal changes. Vision was 20/25 OU. Optos color RG imaging shows virtually normal posterior poles with temporal peripheral retinal hemorrhages. Fluorescein angiography shows temporal ischemia with diffuse vascular staining. Learning Points: The DRCR Retina Network’s Protocol AA found that ultrawidefield (UWF)… Read More
SYPHILIS
This 52YO male presented with a one-week history of blurred central vision in his right eye. There was no past medical history. Vision was 20/200 OD and 20/25 OS. Anterior segments were normal. An oval, whitish submacular lesion is noted OD. Fundus autofluorescence (FAF) reveals much more extensive findings than those noted funduscopically. In particular,… Read More
INHERITED RETINAL DISEASE
This 56YO male has a history of nyctalopia since childhood with a known mutation in the RDS/peripherin gene. Vision was 20/60 in the right eye and counting fingers in the left eye. The patient has been taking vitamin A supplementation. He has an older brother with a more advanced inherited retinal disorder (IRD). Fundus imaging… Read More
LACQUER CRACK
This 33YO highly myopic male presented on 5/18/23 with vision loss in his left eye. Vision was 20/40. Color photography shows a superior macular lacquer crack just superior to a round subretinal hemorrhage. The blood is hyperreflective on Triton swept-source OCT. The blood gradually absorbed with observation. When last examined on 8/23/23, the blood had… Read More
LATTICE DEGENERATION
This 35YO female was referred for asymptomatic lattice degeneration. Vision was 20/20 OU. Optos color RGB imaging of her left eye shows prominent temporal and inferior lattice lesions, some of which are associated with atrophic retinal holes. Similar findings were noted in her right eye (not shown). Learning Points: Lattice lesions have a pocket of… Read More
HRVO
This 63YO male was referred for relatively asymptomatic retinal findings in his left eye. Vision was 20/60. Optos color RG imaging shows a superior hemiretinal vein occlusion (HRVO) with mild hemorrhages, mostly in the temporal periphery. The occlusion is well-perfused without retinal neovascularization on fluorescein angiography. Prominent collateral vessels are noted on the optic disc… Read More
BIETTI CRYSTALLINE DYSTROPHY
This 28YO Egyptian male reported blurry vision, nyctalopia, and photosensitivity. His great-grandmother was blind from an unknown etiology. Vision was 20/40 OD and 20/60 OS. Anterior segments were notable for bilateral limbal crystalline deposits (not shown). Fundus imaging shows extensive subretinal crystalline deposits primarily in the posterior poles bilaterally, with areas of subretinal fibrosis. Fundus… Read More
FOCAL SCLERAL NODULE
This patient presented with an asymptomatic amelanotic lesion inferior to the right optic nerve. OCT scanning through this region shows hyperreflective scleral thickening, which compresses the overlying choroid and elevates the retina. Learning Points: Focal scleral nodule, previously known as solitary idiopathic choroiditis (SIC) and unifocal helioid choroiditis, presents as a single, yellow-white, elevated nodular,… Read More
CRAO WITH CILIORETINAL ARTERY SPARING
This 45YO male presented with acute vision loss in his right eye 4-5 days earlier. Vision was 20/80 in his right eye and 20/20 in his normal left eye. Color photography shows an acute central retinal artery occlusion (CRAO) with sparing of the central and inferior macula due to a large cilioretinal artery. The vertical… Read More
RUPTURED RETINAL ARTERY MACROANEURYSM (RAM)
This 78YO hypertensive female presented with sudden vision loss in her left eye. Vision was 20/40 in her normal right eye and counting fingers in her left eye. Optos color RG imaging shows multiple layers of blood, including a large submacular hemorrhage, intraretinal blood, and preretinal blood. A tiny retinal arterial macroaneurysm is noted in… Read More

