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This 39YO male presented with these asymptomatic subretinal yellow posterior pole lesions. Vision was 20/30 OU. The sharply demarcated yellowish lesions are markedly hyper-autofluorescent. This vitelliform material is hyperreflective on OCT. The subretinal material extends into and elevates the central retina. Learning Points: Best disease is associated with a mutation in the BEST1 gene, which… Read More

This 49YO female presented with several weeks of vision loss in her left eye. A macular neovascularization (MNV) in her right eye was treated 4 years earlier with intravitreal Avastin. Vision was 20/200 OD and 20/70 OS. Both maculas had central pigment loss with intraretinal pigment migration. A small dot of blood was noted inferonasally… Read More

This 54YO male patient presented with asymptomatic bilateral optic nerve conus. Optos color imaging of each eye shows each optic nerve and peripapillary tissue to be sunken from the plane of the surrounding fundus. These findings are captured on OCT. Learning Points: An optic nerve conus is a staphylomatous-like depression of the optic nerve and… Read More

This 48YOF had a history of extensive-stage small-cell lung cancer (SCLC) with metastases to the thoracic and abdominal lymph nodes. She presented to an outside practice with a four-week history of a gradually worsening visual field defect and was diagnosed with cytomegalovirus (CMV) retinitis and started on oral ganciclovir. She was then referred to a… Read More

This 58YO male presented with asymptomatic retinal changes in his right eye. Vision was 20/25 OD. The left eye was phthisical. He had a history of type 2 diabetes. Optos color imaging shows fibrosed retinal neovascularization scattered around the posterior pole. Fluorescein angiography shows scattered retinal neovascularization. We were concerned that panretinal photocoagulation could further… Read More

This 84YO female has stable advanced non-exudative AMD with bilateral macular atrophy (MA). There are numerous classic findings on multimodal imaging of her left eye. Color imaging shows foveal MA. Swept-source OCT shows pericentral outer retinal and RPE atrophy. This atrophy allows for more light to illuminate the underlying choroid and sclera, as well as… Read More

This 72YO male presented with this macula-off rhegmatogenous retinal detachment (RRD). Optos color imaging shows a prominent star fold inferotemporally. This detachment was repaired with vitrectomy and membrane peeling. Learning Points: Proliferative vitreoretinopathy (PVR), which consists of cellular membranes growing on either retinal surface, develops in about 5-10% of retinal detachments. The membranes contract and… Read More

This healthy 32YOF was referred for an asymptomatic lesion in her right macula. Vision was 20/30 OU, and her left fundus was normal. Optos color imaging shows an atrophic, variably pigmented macular colobomatous lesion with a surrounding rim of scalloped pigmentation. Fundus autofluorescence (FAF) shows variable, mostly hypo-FAF, indicating RPE dysfunction/loss. Swept source OCT scanning… Read More

This 50YO male presented with bilateral asymptomatic retinal hemorrhages. He gave a 5-year history of well-controlled type 2 diabetes with a recent A1C of 6.3%, and was previously diagnosed with only mild nonproliferative diabetic retinopathy. Optos imaging shows scattered retinal hemorrhages in all quadrants, most of which are deep with white centers. Mild bilateral macular… Read More

This 52YO male presented with acute visual symptoms in his right eye. Vision was 20/20. Optos imaging shows a non-ischemic central retinal vein occlusion (CRVO) with mild scattered retinal hemorrhages in all quadrants. An acute nasal macular branch retinal artery occlusion (BRAO) is noted, along with a small round patch of congenital hypertrophy of the… Read More