PERSISTENT FETAL VASCULATURE
This healthy 4-month-old girl, born full-term, presented with leukocoria in her right eye that her parents recently noticed. Preoperatively, there was a white central cataract with a clear peripheral zone. B-scan ultrasonography showed a highly reflective stalk that extended from the disc to the periphery with a tent-like elevation over the disc. The left eye… Read More
CHRONIC ICSC WITH MACULAR NEOVASCULARIZATION
This 40YO male has a complex medical history of systemic lupus erythematosus (SLE) and interstitial nephritis, treated with chronic oral corticosteroids and hemodialysis. He presented with two weeks of bilateral vision loss of 1/60 OD and 2/60 OS. Color photography shows extensive pigmentary changes and gutters consistent with chronic multifocal idiopathic central serous chorioretinopathy (ICSC)…. Read More
HARADA DISEASE
This previously healthy 13YO girl presented with several days of bilateral vision loss. Vision was 20/100 OD and 20/400 OS. Optos color RGB imaging shows bilateral multifocal serous exudative retinal detachments. Triton swept-source OCT shows a complex pattern of multifocal pockets of subretinal fluid and bacillary layer detachments (BALAD). The choroid is markedly thickened. Fluorescein… Read More
COATS DISEASE
This healthy 11YO boy was brought in by his parents with a 1.5-year history of vision loss and outward deviation. Vision was 20/15 in his normal OD and light perception OS. Xanthocoria was noted on the pupillary light reflex. Pseudocolor SLO imaging shows extensive peripheral subretinal lipid in all quadrants with telangiectatic and aneurysmal capillary… Read More
BRAF AND MEK INHIBITOR-ASSOCIATED RETINOPATHY
This 67YO male presented with 3 weeks of mild bilateral blurred vision after starting dabrafenib (BRAF inhibitor) and trametinib (MEK inhibitor) for metastatic melanoma. Vision was 20/25 OU. Pseudocolor SLO imaging shows multifocal bilateral macular blisters with serous subretinal fluid, confirmed on OCT. Learning Points: Recent drugs targeting the BRAF and MAPK pathways have emerged… Read More
HYPERTENSIVE RETINOPATHY
This 20YO male has a known history of chronic kidney disease. Despite hemodialysis, he’s had multiple episodes of malignant hypertension over the prior 2 months. He presented with 1 month of severe vision loss of counting fingers at 2 meters OU. Pseudocolor SLO imaging shows profound bilateral disc edema with more peripheral nerve fiber layer… Read More
CHOROIDAL RUPTURE
This 33YO female noted decreased vision in her left eye immediately following blunt trauma when a ceiling an fell on her face. Vision was 20/20 in her normal OD and 20/125 OS. Pseudocolor SLO imaging shows a vertical choroidal rupture bisecting the central macula with surrounding subretinal blood. Radiating retinal striae extend outwards from the… Read More
SYPHILIS
This 61YO female presented with 1 week of vision loss in her left eye. Vision was 20/25 in her normal OD and counting fingers OS. Triton color imaging shows a subretinal yellow-white placoid lesion extending beyond the macula, along with ocular histoplasmosis-related peripapillary scarring. Swept-source OCT shows replacement of the outer retinal bands with hyperreflective… Read More
NORTH CAROLINA MACULAR DYSTROPHY
This 23YO female was referred for bilateral retinal findings. She gave a history of poor VA since early school years. Both her father and paternal grandfather had a history of vision loss since childhood. Vision was 20/60 OD and 20/80 OS. Anterior segments and motility were normal bilaterally. Color photography shows fairly symmetrical variably pigmented… Read More

